Reference summary — not medical advice or a personal risk estimate.
Tobacco smoke
Combustion products from cigarettes, cigars, and pipes — inhaled directly or as secondhand exposure.
Also known as: cigarette smoke, secondhand smoke
What this does NOT mean
Finding a factor documented in this product category does not establish that ordinary use of tobacco smoke causes cancer. It means research — through regulatory testing, recall records, or IARC review — has found that chemical present in this category. Whether it matters for you depends on formulation, dose, frequency, and route of exposure.
What has been documented
- Cadmium and cadmium compoundsIARC Group 1IARC Group 1Contains · high confidence
Present in tobacco leaves; released as aerosol when smoked.
Evidence source: IARC Monograph 100E
- 1,3-ButadieneIARC Group 1IARC Group 1Contains · high confidence
One of the major volatile carcinogens in tobacco smoke.
Evidence source: IARC Monograph 100E
- FormaldehydeIARC Group 1IARC Group 1Contains · high confidence
Combustion byproduct present in every cigarette smoke stream.
Evidence source: IARC Monograph 100E
- BenzeneIARC Group 1IARC Group 1Contains · high confidence
Mainstream and secondhand tobacco smoke contain measurable benzene from incomplete combustion.
Evidence source: IARC Monograph 100E
How to read this page
A factor appearing on this page means it has been documented in this product category — through EPA / FDA testing, IARC monographs, or regulatory recall records. Whether it presents a meaningful personal risk depends on the specific formulation, dose, and how you're exposed. Click any factor to read what science actually says about it, and where.